Abstract - Richard Anderson

While much progress has been made on brain-machine interfaces (BMI) for motor control of a robotic limb, there has been little work on how to provide sensory feedback back to the patient. Such sensory feedback is essential for dexterous control of a prosthetic limb. In this study, we use well-established clinical tools and techniques to provide novel feedback from a virtual-reality arm into the hand area of somatosensory cortex (S1) of human patients to “close the loop” on the motor / sensory pathway. We will study 10 patients undergoing subdural electrocorticography monitoring for epilepsy. In addition to the clinical subdural electrodes needed for seizure detection, we will place an additional mini-subdural grid over the S1 hand area. In the intensive care unit, we will use a clinical cortical stimulator to stimulate the subdural grid to generation artificial sensation. A variety of stimulation parameters will be explored as the patient performs directed behavioral tasks. This study will allow us to better understand how to generate artificial sensation and close the loop for creating a BMI with sensory feedback. This project has been approved by the USC IRB and cleared by the FDA as a non-significant risk device.

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Principal Investigator Institution Title Abstract
Andersen, Richard California Institute of Technology Engineering Artificial Sensation View
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